MDM2 controls the action of p53 tumor suppressor

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  • Photo title: MDM2 controls the action of p53 tumor suppressor
  • Author: Juangaertner
  • Cover photo description:
  • MDM2 violet, foreground binds to p53 blue. Thus, the tumor suppressor p53 cannot bind to DNA and trigger the self-destruction of the cell. In the cytoplasm, a domain of MDM2 and MDMX red add ubiquitin to p53 targeting it for destruction by proteasomes.MDM2 may be a target for cancer chemotherapy
  • Image ID:158071133
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Keywords for Facebook, Twitter and LinkedIn timeline photos

anti apoptosis biochemistry cancer cell chemotherapy damage death division dna enzyme growth mdm2 mutation oncogene oncoprotein p53 peptide protein suppressor tetramer tumor ubiquitin
 
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