RAGE receptor (mouse) hexamer, active form after ligand binding
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  • Photo title: RAGE receptor (mouse) hexamer, active form after ligand binding
  • Author: Juangaertner
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  • RAGE (Advanced glycosylation end product-specific receptor) belongs to the immunoglobulin superfamily and is involved in diabetes, Alzheimer's disease, inflammation and tumour invasion. Oligomerization of RAGE is believed to play an essential role in signal transduction. The position and conformation of the transmembrane and intracellular domains is assumed
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